Across the sciences, enterprise, consumer, fintech, and deep tech, DYDX Capital backs companies solving massive problems with an unfair advantage– the Data High Ground.
Full Portfolio Highlights, Recent First
Tribal
AI-Native Enterprise App Delivery
Tribal AI uses AI agents to deliver trusted enterprise applications grounded in existing systems, with a data high ground of a proprietary ontology of cross-system metadata, starting with Salesforce.
Partnered in 2025
Back to Top
Tess
Enterprise AI Orchestration Platform
Tess AI is an AI orchestration platform that acts as a general contractor for the enterprise AI workforce, with a data high ground of a proprietary Context Moat built across model, user, and organizational interactions.
Partnered in 2026
Tess Website –>
Back to Top
Scentian Bio
Connecting Odorant Receptors with Electrical Signaling for Real-Time Detection
Scentian Bio is building diagnostic tools with groundbreaking sensitivity, with a data high ground of a proprietary dataset mapping protein-chemical interactions across a vast library of odorant receptor responses.
Partnered in 2020
ScentianBio Website –>
Back to Top
CIME Therapeutics
Refining Drug Discovery with a Chemistry-First Approach
CIME has created a high-throughput platform for making complex molecules thousands of times faster than state-of-the-art, with a data high ground of a Build-Test-Learn inference engine that compounds chemical knowledge with every experiment.
Partner since 2025
Back to Top
Immuto Scientific
Native-State Protein Structure Analysis
Immuto Scientific derives native-state protein structures at amino acid resolution for any protein or peptide in weeks, with a data high ground of the world’s most powerful surface protein folding model producing a novel oncology pipeline.
Partnered in 2025
Immuto Website –>
Back to Top
Bruviti
AI Engine for Complex After-Market Service
Bruviti is an agentic AI company that predicts, detects, and resolves complex equipment service issues faster, with a data high ground of a part prediction model trained on technical repair manuals and customer service data
Partnered in 2024
Back to Top
Matterworks
Tools for Understanding and Predicting Biology
Matterworks has built the first large spectral model to automate the interpretation and quantification of mass spectrometry results, with a data high ground of first- and best-in-class proprietary and latent mass spectrometry scans.
Partnered in 2023
Back to Top
Animol
Molecular Discovery For Animal Health
Animol is using a small molecule discovery platform to find safer and more effective animal health drugs, with a data high ground of proprietary access to billions of compound-target interactions overlaid with a generative AI model.
Partnered in 2022
Animol Website ->
Back to Top
Citrine Informatics
Chemical & Materials Development Platform
Citrine is making materials chemistry innovation faster and better, with a data high ground of an AI operating system built upon the universe of known chemical and materials knowledge.
Partnered in 2023
Back to Top
MarketDial
AI Powered Retail Decision Platform
MarketDial is helping retailers comprehensively test and optimize their business initiatives, with a data high ground of a proprietary data-driven decision-making platform built on the largest repository of retail test-and-control experiments.
Partnered in 2022
Back to Top
Berkeley Yeast
Better Yeast through Engineering
Berkeley Yeast is a synthetic biology company engineering new flavors and functions for fermented beverages (including the world’s best non-alcoholic beer), with a data high ground of proprietary datasets from biochemical pathway screening.
Partnered in 2021
Back to Top
Drip Capital
Tech-Enabled Trade Data
Drip Capital is energizing import/export financing between India and the USA, with a data high ground of novel trade credit and marketplace data that creates proprietary risk models unavailable to traditional lenders.
Partnered in 2021
Back to Top
Climate AI
An Enterprise Climate Platform
ClimateAI is safeguarding global supply chains, with a data high ground of the world’s most comprehensive proprietary climate dataset translated into forward-looking enterprise risk intelligence.
Partnered in 2021
Back to Top
Produce Pay
Stabilizing Food Supply Chains
ProducePay is delivering working capital to developing agricultural markets, with a data high ground of farm-level supply chain data and novel credit ratings unavailable through traditional financial channels.
Partnered in 2021
ProducePay Website –>
Back to Top
Enko
Innovating in Agriculture
Enko is finding new sustainable and safe agricultural chemicals, with a data high ground of DNA-encoded libraries and AI-generated chemical interactomes spanning trillions of compound combinations.
Partnered in 2020
Back to Top
Tovala
Fresh Meal Delivery & Smart Ovens
Tovala is changing mealtime with their connected oven and fresh meal service, with a data high ground of a closed-loop data stream from oven usage telemetry that yields unique consumer taste and ordering insights.
Partnered in 2020
Back to Top
Good Eggs
Absurdly Fresh Groceries and Meal-Kits
Good Eggs is delivering the best and freshest grocery experience, with a data high ground of rich customer taste and ordering data curated through a highly differentiated product selection.
Partnered in 2020
Back to Top
Back to Top
AI-Native Enterprise App Delivery
Tribal AI uses AI agents to deliver trusted enterprise applications grounded in existing systems, with a data high ground of a proprietary ontology of cross-system metadata, starting with Salesforce.
Partnered in 2025
Enterprise AI Orchestration Platform
Tess AI is an AI orchestration platform that acts as a general contractor for the enterprise AI workforce, with a data high ground of a proprietary Context Moat built across model, user, and organizational interactions.
Partnered in 2026
Tess Website –>
Connecting Odorant Receptors with Electrical Signaling for Real-Time Detection
Scentian Bio is building diagnostic tools with groundbreaking sensitivity, with a data high ground of a proprietary dataset mapping protein-chemical interactions across a vast library of odorant receptor responses.
Partnered in 2020
ScentianBio Website –>
Refining Drug Discovery with a Chemistry-First Approach
CIME has created a high-throughput platform for making complex molecules thousands of times faster than state-of-the-art, with a data high ground of a Build-Test-Learn inference engine that compounds chemical knowledge with every experiment.
Partner since 2025
Native-State Protein Structure Analysis
Immuto Scientific derives native-state protein structures at amino acid resolution for any protein or peptide in weeks, with a data high ground of the world’s most powerful surface protein folding model producing a novel oncology pipeline.
Partnered in 2025
Immuto Website –>
AI Engine for Complex After-Market Service
Bruviti is an agentic AI company that predicts, detects, and resolves complex equipment service issues faster, with a data high ground of a part prediction model trained on technical repair manuals and customer service data
Partnered in 2024
Tools for Understanding and Predicting Biology
Matterworks has built the first large spectral model to automate the interpretation and quantification of mass spectrometry results, with a data high ground of first- and best-in-class proprietary and latent mass spectrometry scans.
Partnered in 2023
Molecular Discovery For Animal Health
Animol is using a small molecule discovery platform to find safer and more effective animal health drugs, with a data high ground of proprietary access to billions of compound-target interactions overlaid with a generative AI model.
Partnered in 2022
Animol Website ->
Chemical & Materials Development Platform
Citrine is making materials chemistry innovation faster and better, with a data high ground of an AI operating system built upon the universe of known chemical and materials knowledge.
Partnered in 2023
AI Powered Retail Decision Platform
MarketDial is helping retailers comprehensively test and optimize their business initiatives, with a data high ground of a proprietary data-driven decision-making platform built on the largest repository of retail test-and-control experiments.
Partnered in 2022
Better Yeast through Engineering
Berkeley Yeast is a synthetic biology company engineering new flavors and functions for fermented beverages (including the world’s best non-alcoholic beer), with a data high ground of proprietary datasets from biochemical pathway screening.
Partnered in 2021
Tech-Enabled Trade Data
Drip Capital is energizing import/export financing between India and the USA, with a data high ground of novel trade credit and marketplace data that creates proprietary risk models unavailable to traditional lenders.
Partnered in 2021
An Enterprise Climate Platform
ClimateAI is safeguarding global supply chains, with a data high ground of the world’s most comprehensive proprietary climate dataset translated into forward-looking enterprise risk intelligence.
Partnered in 2021
Stabilizing Food Supply Chains
ProducePay is delivering working capital to developing agricultural markets, with a data high ground of farm-level supply chain data and novel credit ratings unavailable through traditional financial channels.
Partnered in 2021
ProducePay Website –>
Innovating in Agriculture
Enko is finding new sustainable and safe agricultural chemicals, with a data high ground of DNA-encoded libraries and AI-generated chemical interactomes spanning trillions of compound combinations.
Partnered in 2020
Fresh Meal Delivery & Smart Ovens
Tovala is changing mealtime with their connected oven and fresh meal service, with a data high ground of a closed-loop data stream from oven usage telemetry that yields unique consumer taste and ordering insights.
Partnered in 2020
Absurdly Fresh Groceries and Meal-Kits
Good Eggs is delivering the best and freshest grocery experience, with a data high ground of rich customer taste and ordering data curated through a highly differentiated product selection.
Partnered in 2020
In 2014 the world began to analyze and understand unstructured data at scale…a decade later AI has supercharged these endeavors.
At DYDX Capital, we believe that data-driven technologies and the founders building them are the best route to deliver on our mission.
We are at the beginning of this opportunity and it will scale over the coming decades. The DYDX Capital team would love to learn about what you are building.
To find these big opportunities it requires a healthy obsession with the problems affecting global populations and massive value chains. That’s where we spend the majority of our time and where we continue to build deep expertise and even deeper relationships, so that we can help scale solutions that change lives everywhere.
Our team loves to understand how a business is defensible and durable. We also love to talk about the technology and how the product is driven to new heights by data analysis. But most of all we enjoy meeting a purpose-built team that has exceptional “entrepreneur – market fit” that can easily answer the question, “Why is this the right team to do this?”. It is a question we ask ourselves. If you are building an incredible business we’d love to hear from you.